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Recurrent aphthous ulcers are common painful mucosal conditions affecting the oral cavity. Despite their high prevalence, etiopathogenesis remains unclear. So as a result, the available treatments still remaining unsatisfactory with the ability to reduce the severity, healing time and the frequency of recurrence of ulceration with no permanent and definitive treatment. The healing time ranges usually from seven to fourteen days. This review discusses the different treatment modalities and updates that are available to the moment and according to the severity of the ulceration, the clinician can decide to go with topical, physical or systemic treatments which give the clinician broad and detailed picture to deal with RAS in an appropriate way. This review article summarizes the clinical presentation, diagnostic criteria, and recent trends in the management of recurrent apthous stomatitis.

Diagnostic criteria; immunomodulators; recurrent apthous stomatitis.