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In recent years, pulp revascularization has emerged as a novel approach to treat periapical disease in young permanent immature teeth. The protocol focuses on thorough irrigation and disinfection with minimal mechanical instrumentation, thereby allowing stem cells from apical papilla (SCAP) to repopulate the canal and facilitating continued root development, with consistently favorable outcomes. This case report describes the management of a necrotic immature left mandibular second premolar of 16 year old female. The clinical examination, radiographic assessment, and cone-beam computed tomography (CBCT) findings indicated an immature mandibular left second premolar with periapical radiolucency, which was managed using a revascularization procedure with Platelet-rich fibrin as the scaffold. At 3, 6 and 12 months follow-up, patient was asymptomatic clinically and showed significant radiographic healing and reduction in size. This case report highlights the importance of an alternative modality for managing periapical lesions in immature permanent teeth.

Immature teeth; mineral trioxide aggregate; platelet-rich fibrin; pulp revascularization; regenerative endodontics.